1239279-30-1
1239279-30-1
Chemical Structure
SSR-241586
- CAS No.: 1239279-30-1
- Formula:C32H42Cl2N4O3
- Molecular Weight:601.61
IUPAC Name: (R)-1'-(2-(4-benzoyl-2-(3,4-dichlorophenyl)morpholin-2-yl)ethyl)-N,N-dimethyl-[1,4'-bipiperidine]-4'-carboxamide
InChIKey: RVQZVVJLIUXDPN-YTTGMZPUSA-N
SMILES: O=C(C1(N2CCCCC2)CCN(CC[C@@]3(C4=CC=C(Cl)C(Cl)=C4)CN(C(C5=CC=CC=C5)=O)CCO3)CC1)N(C)C
Biological Activity: SSR-241586 is an antagonist of neurokinin receptors. SSR-241586 is shown to be active in the treatment of depression, schizophrenia, urinary trouble, emesis, and irritable bowel syndrome (IBS)[1][2].
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SSR-241586 | SSR-241586 is an antagonist of neurokinin receptors. SSR-241586 is shown to be active in the treatment of depression, schizophrenia, urinary trouble, emesis, and irritable bowel syndrome (IBS). | |||||||||||||||||||||
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References
- [1]. Métro TX, et al. Asymmetric synthesis of an antagonist of neurokinin receptors: SSR 241586. J Org Chem. 2011 Apr 15;76(8):2594-602. [Content Brief]
- [2]. Cochi A, et al. Enantioselective synthesis of SSR 241586 by using an organo-catalyzed Henry reaction. Org Lett. 2010 Aug 20;12(16):3693-5. [Content Brief]
