1240857-57-1
1240857-57-1
Chemical Structure
CD28-IN-2
- CAS No.: 1240857-57-1
- Formula:C19H17FN2O3
- Molecular Weight:340.35
InChIKey: GUMYBTUCIGUOQI-UHFFFAOYSA-N
SMILES: COC1=CC=C(CC(OCC2=CC=C(C=C2)N3C=CC=N3)=O)C=C1F
Biological Activity: CD28-IN-2 is a selective CD28-B7 interaction (IC50: 22.4 μM) inhibitor that binds directly to CD28, with a Kd value of 24.1 μM. CD28-IN-2 inhibits CD28-driven immune activation and blocks T cell costimulation. CD28-IN-2 can be used for the study of antitumor immunity and immune-related disorders[1].
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CD28-IN-2 | CD28-IN-2 is a selective CD28-B7 interaction (IC50: 22.4 μM) inhibitor that binds directly to CD28, with a Kd value of 24.1 μM. CD28-IN-2 inhibits CD28-driven immune activation and blocks T cell costimulation. CD28-IN-2 can be used for the study of antitumor immunity and immune-related disorders. | |||||||||||||||||||||
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