1246560-33-7
1246560-33-7
Chemical Structure
VS-5584
Synonym(s): SB2343
- CAS No.: 1246560-33-7
- Formula:C17H22N8O
- Molecular Weight:354.41
IUPAC Name: 5-(9-isopropyl-8-methyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
InChIKey: QYBGBLQCOOISAR-UHFFFAOYSA-N
SMILES: NC1=NC=C(C2=C3N=C(C)N(C(C)C)C3=NC(N4CCOCC4)=N2)C=N1
Biological Activity: VS-5584 is a pan-PI3K/mTOR kinase inhibitor with IC50s of 16 nM, 68 nM, 42 nM, 25 nM, and 37 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR, respectively. VS-5584 simultaneously blocks mTORC2 as well as mTORC1.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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VS-5584 | 98.71% | VS-5584 is a pan-PI3K/mTOR kinase inhibitor with IC50s of 16 nM, 68 nM, 42 nM, 25 nM, and 37 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR, respectively. VS-5584 simultaneously blocks mTORC2 as well as mTORC1. | ||||||||||||||||||||
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