124886-01-7
124886-01-7
Chemical Structure
BMY 20844
- CAS No.: 124886-01-7
- Formula:C12H11N3O
- Molecular Weight:213.24
IUPAC Name: 7,8-dimethyl-1,4-dihydro-2H-imidazo[4,5-b]quinolin-2-one
InChIKey: ODCKPUDNMNCWMR-UHFFFAOYSA-N
SMILES: O=C1N=C2NC3=CC=C(C)C(C)=C3C=C2N1
Biological Activity: BMY 20844 is an orally active platelet cAMP phosphodiesterase inhibitor with anti-thrombosis activity. BMY 20844 can elevate cAMP levels and activate protein kinase in platelets. BMY 20844 can be used for the research of cardiovascular disease[1][2].
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BMY 20844 | BMY 20844 is an orally active platelet cAMP phosphodiesterase inhibitor with anti-thrombosis activity. BMY 20844 can elevate cAMP levels and activate protein kinase in platelets. BMY 20844 can be used for the research of cardiovascular disease. | |||||||||||||||||||||
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References
- [1]. Seiler S, et al. Imidazoquinoline derivatives: potent inhibitors of platelet cAMP phosphodiesterase which elevate cAMP levels and activate protein kinase in platelets. Thromb Res. 1991 Apr;62(1-2):31-42. [Content Brief]
- [2]. Buchanan JO, et al. Pharmacology of a potent, new antithrombotic agent, 1,3-dihydro-7,8-dimethyl-2H-imidazo[4,5-b]quinolin-2-one (BMY-20844). Thromb Res. 1989 Nov 1;56(3):333-46. [Content Brief]
