1251542-88-7
1251542-88-7
Chemical Structure
CHD1L-IN-2
- CAS No.: 1251542-88-7
- Formula:C24H24N6O
- Molecular Weight:412.50
IUPAC Name: N-(4-((6-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-yl)amino)phenyl)-1H-indole-3-carboxamide
InChIKey: QDJGAYMHWIYFFE-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(C=C1)NC2=NC(=NC(=C2)C)N3CCCC3)C4=CNC=5C=CC=CC54
Biological Activity: CHD1L-IN-2 is a CHD1L inhibitor and exhibits cytotoxicity against tumor cells[1][2].
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CHD1L-IN-2 | CHD1L-IN-2 is a CHD1L inhibitor and exhibits cytotoxicity against tumor cells. | |||||||||||||||||||||
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References
- [1]. Daniel V. LABARBERA, et al. Small molecule inhibitors of oncogenic chd1l with preclinical activity against colorectral cancer. WO2023055763A2. 2023-04-06.
- [2]. Prigaro BJ, et al. Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L. J Med Chem. 2022 Mar 10;65(5):3943-3961. [Content Brief]
