1253291-12-1
1253291-12-1
Chemical Structure
GRN-529
- CAS No.: 1253291-12-1
- Formula:C22H15F2N3O2
- Molecular Weight:391.37
IUPAC Name: (4-(difluoromethoxy)-3-(pyridin-2-ylethynyl)phenyl)(5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)methanone
InChIKey: JITMSIRHBAVREW-UHFFFAOYSA-N
SMILES: O=C(N1CC2=NC=CC=C2C1)C3=CC=C(C(C#CC4=NC=CC=C4)=C3)OC(F)F
Biological Activity: GRN-529 is a negative allosteric modulator (NAM) for mGluR5. GRN-259 modulates sleep-wake activity, and exhibits anxiolytic efficacy in rats[1].
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GRN-529 | GRN-529 is a negative allosteric modulator (NAM) for mGluR5. GRN-259 modulates sleep-wake activity, and exhibits anxiolytic efficacy in rats. | |||||||||||||||||||||
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