125527-24-4
Chemical Structure
Butyryl-Coenzyme A sodium
Synonym(s): Butyryl CoA sodium
- CAS No.: 125527-24-4
- Formula:C25H41N7NaO17P3S
- Molecular Weight:859.61
IUPAC Name: sodium (2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-2-(((((((R)-4-((3-((2-(butyrylthio)ethyl)amino)-3-oxopropyl)amino)-3-hydroxy-2,2-dimethyl-4-oxobutoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)methyl)-4-hydroxytetrahydrofuran-3-yl hydrogen phosphate
InChIKey: XBNZETGNIJRVAR-XXXNBSBMSA-M
SMILES: O[C@H]([C@@H]1O[P](O)(O[Na])=O)[C@](O[C@@H]1CO[P](O[P](OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CCC)=O)=O)=O)(O)=O)(O)=O)([H])N2C3=NC=NC(N)=C3N=C2
Biological Activity: Butyryl-Coenzyme A (Butyryl CoA) sodium is a short-chain acyl-coenzyme A compound, and is also a substrate for histone H3K9 butyrylation and an intermediate metabolite of fatty acid β-oxidation. Butyryl-Coenzyme A sodium can be used in research on cardiac hypertrophy[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Butyryl-Coenzyme A sodium | 96.91% | Butyryl-Coenzyme A (Butyryl CoA) sodium is a short-chain acyl-coenzyme A compound, and is also a substrate for histone H3K9 butyrylation and an intermediate metabolite of fatty acid β-oxidation. Butyryl-Coenzyme A sodium can be used in research on cardiac hypertrophy. | ||||||||||||||||||||
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References
- [1]. Yang Z, et al. Histone H3K9 butyrylation is regulated by dietary fat and stress via an Acyl-CoA dehydrogenase short chain-dependent mechanism. Molecular metabolism. 2021 Nov;53:101249.
- [2]. Gates LA, et al. Histone butyrylation in the mouse intestine is mediated by the microbiota and associated with regulation of gene expression. Nature metabolism. 2024 Apr;6(4):697-707.
- [3]. Duncan SH, et al. Acetate utilization and butyryl coenzyme A (CoA):acetate-CoA transferase in butyrate-producing bacteria from the human large intestine. Applied and environmental microbiology. 2002 Oct;68(10):5186-90.
- [4]. Hartmanis MG, et al. Intermediary Metabolism in Clostridium acetobutylicum: Levels of Enzymes Involved in the Formation of Acetate and Butyrate. Applied and environmental microbiology. 1984 Jun;47(6):1277-83.
- [5]. Sato M, et al. Three CoA Transferases Involved in the Production of Short Chain Fatty Acids in Porphyromonas gingivalis. Frontiers in microbiology. 2016;7:1146. [Content Brief]
