1255516-86-9
1255516-86-9
Chemical Structure
MS-1020
- CAS No.: 1255516-86-9
- Formula:C21H18N2O3
- Molecular Weight:346.38
IUPAC Name: 1-hydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-2-naphthamide
InChIKey: KHJNISGKGIHTMY-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C2C=CC=CC2=C1O)NCCC3=CNC4=C3C=C(O)C=C4
Biological Activity: MS-1020 is a potent and ATP-competitive JAK3 inhibitor. MS-1020 inhibits JAK3/STAT signaling and induces apoptosis. MS-1020 promotes cell death. MS-1020 decreases the expression of tyrosine phosphorylated STAT3 levels. MS-1020 has the potential for the research of cancers harboring aberrant JAK3 signaling[1].
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MS-1020 | MS-1020 is a potent and ATP-competitive JAK3 inhibitor. MS-1020 inhibits JAK3/STAT signaling and induces apoptosis. MS-1020 promotes cell death. MS-1020 decreases the expression of tyrosine phosphorylated STAT3 levels. MS-1020 has the potential for the research of cancers harboring aberrant JAK3 signaling. | |||||||||||||||||||||
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