125720-21-0
Chemical Structure
Fibronectin Adhesion-promoting Peptide
Synonym(s): Heparin Binding Peptide
- CAS No.: 125720-21-0
- Formula:C47H74N16O10
- Molecular Weight:1023.19
IUPAC Name: L-tryptophyl-L-glutaminyl-L-prolyl-L-prolyl-L-arginyl-L-alanyl-L-arginyl-L-isoleucine
InChIKey: OVXIMRGEBNSORH-PJRZOMOUSA-N
SMILES: CC[C@H](C)[C@@H](C(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@H]1N(C([C@H]2N(C([C@H](CCC(N)=O)NC([C@H](CC3=CNC4=C3C=CC=C4)N)=O)=O)CCC2)=O)CCC1)=O)=O)=O)=O
Biological Activity: Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin. It promotes assembly of mesenchymal stem cell (MSC) spheroids into larger aggregates. Fibronectin Adhesion-promoting Peptide directly promotes the adhesion, spreading, and migration of endothelial cells by reacting with heparin binding domains of cells[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Fibronectin Adhesion-promoting Peptide | 98.50% | Fibronectin Adhesion-promoting Peptide (Heparin Binding Peptide) is one of the heparin-binding amino acid sequences found in the carboxy-terminal heparin-binding domain of fibronectin. It promotes assembly of mesenchymal stem cell (MSC) spheroids into larger aggregates. Fibronectin Adhesion-promoting Peptide directly promotes the adhesion, spreading, and migration of endothelial cells by reacting with heparin binding domains of cells. | ||||||||||||||||||||
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References
- [1]. Hoesli CA, et al. A fluorophore-tagged RGD peptide to control endothelial cell adhesion to micropatterned surfaces. Biomaterials. 2014 Jan;35(3):879-90. [Content Brief]
- [2]. Chollet C, et al. Impact of peptide micropatterning on endothelial cell actin remodeling for cell alignment under shear stress. Macromol Biosci. 2012 Dec;12(12):1648-59. [Content Brief]
