1259536-62-3
1259536-62-3
Chemical Structure
QO 58
- CAS No.: 1259536-62-3
- Formula:C18H8Cl2F4N4O
- Molecular Weight:443.18
IUPAC Name: 5-(2,6-dichloro-5-fluoropyridin-3-yl)-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
InChIKey: JEXACLGXUUYXDX-UHFFFAOYSA-N
SMILES: O=C1C=C(C2=C(Cl)N=C(Cl)C(F)=C2)NC3=C(C(C(F)(F)F)=NN13)C4=CC=CC=C4
Biological Activity: QO 58 is a potent modulator of K(v)7 channels. QO-58 increases the current amplitudes, shifts the voltage-dependent activation curve in a more negative direction and slows the deactivation of K(v)7.2/K(v)7.3 currents. QO-58 has the potential for the research of diseases associated with neuronal hyperexcitability[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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QO 58 | 99.01% | QO 58 is a potent modulator of K(v)7 channels. QO-58 increases the current amplitudes, shifts the voltage-dependent activation curve in a more negative direction and slows the deactivation of K(v)7.2/K(v)7.3 currents. QO-58 has the potential for the research of diseases associated with neuronal hyperexcitability. | ||||||||||||||||||||
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QO 58 (Standard) | ≥98% | QO 58 (Standard) is the analytical standard of QO 58 (HY-110162). This product is intended for research and analytical applications. QO 58 is a potent modulator of K(v)7 channels. QO-58 increases the current amplitudes, shifts the voltage-dependent activation curve in a more negative direction and slows the deactivation of K(v)7.2/K(v)7.3 currents. QO-58 has the potential for the research of diseases associated with neuronal hyperexcitability. | ||||||||||||||||||||
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