1260231-06-8
1260231-06-8
Chemical Structure
17β-Estradiol-3-β-D-glucuronide-d3
- CAS No.: 1260231-06-8
- Formula:C24H29D3O8
- Molecular Weight:451.52
IUPAC Name: (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(((8R,9S,13S,14S,17S)-17-hydroxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-3-yl-16,16,17-d3)oxy)tetrahydro-2H-pyran-2-carboxylic acid
InChIKey: MUOHJTRCBBDUOW-NCKPPFHHSA-N
SMILES: C[C@@]12[C@](CC([2H])([2H])[C@]2([2H])O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5O)O)O)C(O)=O)C=C4CC3
Biological Activity: 17β-Estradiol-3-β-D-glucuronide-d3 is the deuterium labeled 17β-Estradiol-3-β-D-glucuronide[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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17β-Estradiol-3-β-D-glucuronide-d3 | 98.45% | 17β-Estradiol-3-β-D-glucuronide-d3 is the deuterium labeled 17β-Estradiol-3-β-D-glucuronide. | ||||||||||||||||||||
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Estradiol 3-glucuronide | 97.62% | Estradiol 3-glucuronide is an estrogen metabolite, which is a glucuronide conjugate formed from Estradiol (HY-B0141) via catalysis by uridine diphosphate glucuronosyltransferases in tissues such as the liver. Estradiol 3-glucuronide is a potent substrate of Mrp2, with an S50 value of 55.7 μM. Estradiol 3-glucuronide achieves hepatobiliary transport in hepatocytes through basolateral uptake via OATP1B1, OATP1B3 and OATP2B1, as well as apical efflux via MRP2 and BCRP. | ||||||||||||||||||||
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Estriol 16α-(β-D-glucuronide) | Estriol 16α-(β-D-glucuronide) is an endogenous metabolite present in Urine that can be used for the research of Pregnancy. | |||||||||||||||||||||
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Estrone 3-glucuronide | Estrone 3-glucuronide is a dominant urinary metabolite of Estradiol (HY-B0141) and urinary marker for female fertile window prediction. Estrone 3-glucuronide can be used in combination with luteinizing hormone in ovulation prediction kits. | |||||||||||||||||||||
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Estriol 3-glucuronide | Estriol-3-glucuronide exists in amniotic fluid during normal pregnancy and occurs naturally in urine. | |||||||||||||||||||||
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Ethynyl estradiol 3-b-D-glucuronide | Ethynyl estradiol 3-bD-glucuronide is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-Glycan recognition and the role of glycans in biological systems. This field is closely related to basic research, biomedicine and biotechnology. | |||||||||||||||||||||
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Estriol 3-glucuronide sodium salt | 99.76% | Estriol 3-glucuronide (Estriol 3-β-D-Glucuronide) sodium salt is a metabolite of Estriol. Estriol 3-glucuronide sodium salt competitively inhibits the hydrolysis of 4-methylumbelliferyl-β-D-glucuronide (4Mu-GlcU). Estriol 3-glucuronide sodium salt is a substrate for hydrolysis by Klotho-human IgG1 Fc protein (KLFc). | ||||||||||||||||||||
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2-Methoxy-estradiol-17beta 3-glucuronide | 2-Methoxy-estradiol-17beta 3-glucuronide is a nucleoside metabolite. | |||||||||||||||||||||
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Estradiol 3-glucuronide sodium | 99.9% | Estradiol 3-glucuronide sodium is an estrogen metabolite, which is a glucuronide conjugate formed by the catalysis of uridine diphosphate glucuronosyltransferase in tissues such as the liver from Estradiol (HY-B0141). Estradiol 3-glucuronide sodium is a potent substrate of Mrp2, with an S50 of 55.7 μM. Estradiol 3-glucuronide sodium achieves hepatobiliary transport in hepatocytes through basolateral uptake via OATP1B1, OATP1B3 and OATP2B1, as well as apical efflux via MRP2 and BCRP. | ||||||||||||||||||||
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Estrone 3-glucuronide sodium | 98.30% | Estrone 3-glucuronide sodium is a metabolite of 17-Estradiol. | ||||||||||||||||||||
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Estradiol 17-(β-D-Glucuronide) | 99.0% | Estradiol 17-(β-D-Glucuronide) is a D-ring glucuronide metabolite of natural estrogen formed in the liver. Estradiol 17-(β-D-Glucuronide) is a substrate of the organic anion-transporting polypeptide family (Oatp) and multidrug resistance-associated protein 2 (Mrp2). Estradiol 17-(β-D-Glucuronide) regulates MRP8-mediated transport processes and inhibits MRP8-mediated transport of dehydroepiandrosterone 3-sulfate and taurocholic acid. Estradiol 17-(β-D-Glucuronide) induces immediate, reversible reduction of bile flow and acute intrahepatic cholestasis in female rats without altering the bile acid composition in bile. Estradiol 17-(β-D-Glucuronide) can be used in studies related to intrahepatic cholestasis. | ||||||||||||||||||||
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