126111-99-7
Chemical Structure
Rhodamine-DHPE
- CAS No.: 126111-99-7
- Formula:C70H117N4O14PS2
- Molecular Weight:1333.80
InChIKey: LXFSNBISPJBDRA-KINGROEASA-N
SMILES: CCN(CC)CC.O=S([O-])(C1=C(C=CC(S(NCCOP(OC[C@H](OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)(O)=O)(=O)=O)=C1)C2=C(C=CC(N(CC)CC)=C3)C3=[O+]C4=C2C=CC(N(CC)CC)=C4)=O
Biological Activity: Rhodamine-DHPE is a fluorescently labeled phosphatidylethanolamine lipid that labels phospholipid bilayers. Rhodamine-DHPE serves as a fluorescence quenching substrate and membrane stain. The fluorescence lifetime of Rhodamine-DHPE decreases significantly in the presence of Cu2+-PS complexes. Rhodamine-DHPE effectively stains the membranes of human red blood cells and mouse fibroblasts, and supports lifetime-resolved imaging via pump-probe fluorescence microscopy[1][2][3].
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Rhodamine-DHPE | Rhodamine-DHPE is a fluorescently labeled phosphatidylethanolamine lipid that labels phospholipid bilayers. Rhodamine-DHPE serves as a fluorescence quenching substrate and membrane stain. The fluorescence lifetime of Rhodamine-DHPE decreases significantly in the presence of Cu2+-PS complexes. Rhodamine-DHPE effectively stains the membranes of human red blood cells and mouse fibroblasts, and supports lifetime-resolved imaging via pump-probe fluorescence microscopy. | |||||||||||||||||||||
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References
- [1]. Simonsson L, et al. Continuous lipid bilayers derived from cell membranes for spatial molecular manipulation. J Am Chem Soc. 2011;133(35):14027-14032. [Content Brief]
- [2]. Poyton M F. Metallomembranes: Characterizing Transition Metal Ion-Lipid Complexes[J]. 2016.
- [3]. Dong CY, et al. Fluorescence lifetime imaging by asynchronous pump-probe microscopy. Biophys J. 1995;69(6):2234-2242. [Content Brief]
