1261432-05-6
1261432-05-6
Chemical Structure
(E/Z)-N-Desethylsunitinib hydrochloride
Synonym(s): (E/Z)-SU-12662 hydrochloride
- CAS No.: 1261432-05-6
- Formula:C20H24ClFN4O2
- Molecular Weight:406.88
InChIKey: WJMIVJQUMZPBDC-GYVLLFFHSA-N
SMILES: O=C1NC2=CC=C(C=C2/C1=C\C3=C(C)C(C(NCCNCC)=O)=C(C)N3)F.Cl
Biological Activity: (E/Z)-N-Desethylsunitinib hydrochloride ((E/Z)-SU-12662 hydrochloride) is a compound with potential anti-tumor activity that inhibits VEGF-R2 and PDGF-Rβ tyrosine kinases. (E/Z)-N-Desethylsunitinib hydrochloride is the main active metabolite of sunitinib and has the ability to competitively inhibit ATP[1].
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(E/Z)-N-Desethylsunitinib hydrochloride | (E/Z)-N-Desethylsunitinib hydrochloride ((E/Z)-SU-12662 hydrochloride) is a compound with potential anti-tumor activity that inhibits VEGF-R2 and PDGF-Rβ tyrosine kinases. (E/Z)-N-Desethylsunitinib hydrochloride is the main active metabolite of sunitinib and has the ability to competitively inhibit ATP. | |||||||||||||||||||||
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