1262406-08-5
1262406-08-5
Chemical Structure
p38α inhibitor 4
- CAS No.: 1262406-08-5
- Formula:C14H7F6N3O
- Molecular Weight:347.22
IUPAC Name: 4-(trifluoromethyl)-3-(3-(trifluoromethyl)phenyl)-1,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one
InChIKey: YEINPIKXEQEWSU-UHFFFAOYSA-N
SMILES: O=C1C=C(C(F)(F)F)C2=C(NN=C2C3=CC(C(F)(F)F)=CC=C3)N1
Biological Activity: p38α inhibitor 4 (compound 10) is a selective and allosteric p38α inhibitor with an IC50 value of 1.2 μM. p38α inhibitor 4 exhibits no activity against p38β, p38γ, and p38δ[1].
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p38α inhibitor 4 | p38α inhibitor 4 (compound 10) is a selective and allosteric p38α inhibitor with an IC50 value of 1.2 μM. p38α inhibitor 4 exhibits no activity against p38β, p38γ, and p38δ. | |||||||||||||||||||||
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