1263893-98-6
1263893-98-6
Chemical Structure
zr17-2
- CAS No.: 1263893-98-6
- Formula:C13H20N6O2S
- Molecular Weight:324.40
IUPAC Name: 2-((2-amino-9-(2-(diethylamino)ethyl)-9H-purin-6-yl)thio)acetic acid
InChIKey: QYTOGPUSMCMAMH-UHFFFAOYSA-N
SMILES: O=C(O)CSC1=C2N=CN(CCN(CC)CC)C2=NC(N)=N1
Biological Activity: zr17-2 is a cold inducible RNA-binding protein (CIRBP) agonist. zr17-2 has anti-inflammatory and anti-oxidant and can be used for the study of myocardial infarction. zr17-2 is a hypothermia mimetic molecule that reduces oxidative stress-induced retinal cell death[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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zr17-2 | 98.01% | zr17-2 is a cold inducible RNA-binding protein (CIRBP) agonist. zr17-2 has anti-inflammatory and anti-oxidant and can be used for the study of myocardial infarction. zr17-2 is a hypothermia mimetic molecule that reduces oxidative stress-induced retinal cell death. | ||||||||||||||||||||
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References
- [1]. Contartese DS, et al. A hypothermia mimetic molecule (zr17-2) reduces ganglion cell death and electroretinogram distortion in a rat model of intraorbital optic nerve crush (IONC). Front Pharmacol. 2023 Jan 23;14:1112318. [Content Brief]
- [2]. Zhang J, et al. Upregulation of CIRP by its agonist prevents the development of heart failure in myocardial infarction rats. BMC Cardiovasc Disord. 2024 Mar 27;24(1):185. [Content Brief]
