126456-43-7
126456-43-7
Chemical Structure
(1S,2R)-1-Aminoindan-2-ol
- CAS No.: 126456-43-7
- Formula:C9H11NO
- Molecular Weight:149.19
IUPAC Name: (1S,2R)-1-amino-2,3-dihydro-1H-inden-2-ol
InChIKey: LOPKSXMQWBYUOI-BDAKNGLRSA-N
SMILES: O[C@H]1[C@@H](N)C2=C(C=CC=C2)C1
Biological Activity: (1S,2R)-1-Aminoindan-2-ol is a chiral resolving agent. (1S,2R)-1-Aminoindan-2-ol efficiently resolves various racemic 2-arylalkanoic acids and precisely controls the stereostructure of the products in asymmetric syntheses. (1S,2R)-1-Aminoindan-2-ol can be used in the synthesis of HIV protease inhibitors[1][2].
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(1S,2R)-1-Aminoindan-2-ol | 99.96% | (1S,2R)-1-Aminoindan-2-ol is a chiral resolving agent. (1S,2R)-1-Aminoindan-2-ol efficiently resolves various racemic 2-arylalkanoic acids and precisely controls the stereostructure of the products in asymmetric syntheses. (1S,2R)-1-Aminoindan-2-ol can be used in the synthesis of HIV protease inhibitors. | ||||||||||||||||||||
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References
- [1]. Kinbara K, et al. Chiral discrimination of 2-arylalkanoic acids by (1 S, 2 R)-1-aminoindan-2-ol through the formation of a consistent columnar supramolecular hydrogen-bond network. Journal of the Chemical Society, Perkin Transactions 2, 2000 (1): 111-119.
- [2]. Ghosh AK, et al. Transition-State Mimetics for HIV Protease Inhibitors: Stereocontrolled Synthesis of Hydroxyethylene and Hydroxyethylamine Isosteres by Ester-Derived Titanium Enolate Syn and Anti-Aldol Reactions. J Org Chem. 1998 Sep 4;63(18):6146-6152. [Content Brief]
