1264748-47-1
Chemical Structure
WH-15
- CAS No.: 1264748-47-1
- Formula:C31H43N2O18P3
- Molecular Weight:824.60
IUPAC Name: 4-((hydroxy(((1S,2S,3R,4S,5S,6R)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl)oxy)phosphoryl)oxy)-3-(octyloxy)benzyl quinolin-6-ylcarbamate
InChIKey: HMMZQMXOCSQOIR-HPSFBBAHSA-N
SMILES: O[C@@H]1[C@H](OP(O)(OC2=CC=C(COC(NC3=CC=C4N=CC=CC4=C3)=O)C=C2OCCCCCCCC)=O)[C@@H](O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@@H]1O
Biological Activity: WH-15 is a fluorogenic PLC reporter with Km value of 49; 30, 86.1 µM for PLC-γ1, PLC-δ1, PLC-β2, respectively. WH-15 can be cleaved in a cascade reaction to generate fluorescent 6-aminoquinoline. WH-15 can be used to respond to imaging PLC activity in live cells (Ex/Em = ~344/530 nm)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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WH-15 | 99.51% | WH-15 is a fluorogenic PLC reporter with Km value of 49; 30, 86.1 µM for PLC-γ1, PLC-δ1, PLC-β2, respectively. WH-15 can be cleaved in a cascade reaction to generate fluorescent 6-aminoquinoline. WH-15 can be used to respond to imaging PLC activity in live cells (Ex/Em = ~344/530 nm). | ||||||||||||||||||||
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Stafib-1 | 99.25% | Stafib-1 is the first selective inhibitor of the STAT5b SH2 domain, with a Ki of 44 nM and an IC50 of 154 nM. | ||||||||||||||||||||
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Stafib-2 | 99.97% | Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b, with an IC50 of 82 nM and 1.7 μM for STAT5b and STAT5a, respectively. Stafib-2 exhibits poor cell permeability. | ||||||||||||||||||||
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PtdIns-(3,4,5)-P3(1,2-dihexanoyl) ammonium | PtdIns-(3,4,5)-P3(1,2-dihexanoyl) ammonium (compound 850176) is a vaccine adjuvant that enhances the immune function of vaccines. | |||||||||||||||||||||
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PtdIns-(4,5)-P2 (1,2-dioctanoyl) | PtdIns-(4,5)-P2 (1,2-dioctanoyl) is a phosphatidylinositol derivative that binds to ABCB5. | |||||||||||||||||||||
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06:0 PI(3,5)P2 ammonium | 06:0 PI(3,5)P2 (PIP2[3',5'](6:0/6:0)) ammonium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery. | |||||||||||||||||||||
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08:0 PI(4,5)P2 ammonium | 08:0 PI(4,5)P2 ammonium is suitable for identifying its binding site at the transient receptor potential vanilloid 4 (TRPV 4 N) terminus. | |||||||||||||||||||||
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diC8PI(3,5)P2 triammonium | diC8PI(3,5)P2 (08:0 PI(3,5)P2) triammonium is a lipid that can be used to prepare lipid nanoparticles (LNPs) for drug delivery. | |||||||||||||||||||||
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08:0 PI(3,4)P2 | 08:0 PI(3,4)P2 (1,2-Dioctanoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′-bisphosphate) (ammonium)) is a kind of biochemical reagent. | |||||||||||||||||||||
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1,2-Dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) ammonium | 1,2-Dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) ammonium is a membrane-bound signaling molecule with activities that regulate cell growth, metabolism, proliferation, and survival. 1,2-Dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) ammonium plays an important role in cell physiology and participates in multiple signal transduction pathways. 1,2-Dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-trisphosphate) ammonium has a profound effect on intracellular signaling. | |||||||||||||||||||||
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Phosphatidylinositol bis-4,5-phosphate, 1,2-dioctanoyl sodium | Phosphatidylinositol bis-4,5-phosphate, 1,2-dioctanoyl sodiumis a phosphatidylinositol derivative that binds to ABCB5. | |||||||||||||||||||||
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