1266212-81-0
1266212-81-0
Chemical Structure
A-887826
- CAS No.: 1266212-81-0
- Formula:C26H29ClN4O3
- Molecular Weight:480.99
IUPAC Name: 5-(4-butoxy-3-chlorophenyl)-N-((2-morpholinopyridin-3-yl)methyl)nicotinamide
InChIKey: JPJGFWKHSMUKFO-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C2=CC=C(OCCCC)C(Cl)=C2)=CN=C1)NCC3=CC=CN=C3N4CCOCC4
Biological Activity: A-887826 is a potent, selective, oral bioavailable and voltage-dependent Na(v)1.8 sodium channel blocker with an IC50 of 11 nM . A-887826 attenuates neuropathic tactile allodynia in vivo[1].
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A-887826 | 99.10% | A-887826 is a potent, selective, oral bioavailable and voltage-dependent Na(v)1.8 sodium channel blocker with an IC50 of 11 nM . A-887826 attenuates neuropathic tactile allodynia in vivo. | ||||||||||||||||||||
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A-887826 (Standard) | ≥98% | A-887826 (Standard) is the analytical standard of A-887826 (HY-100080). This product is intended for research and analytical applications. A-887826 is a potent, selective, oral bioavailable and voltage-dependent Na(v)1.8 sodium channel blocker with an IC50 of 11 nM . A-887826 attenuates neuropathic tactile allodynia in vivo. | ||||||||||||||||||||
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