1268513-27-4
Chemical Structure
CTP-NBD
- CAS No.: 1268513-27-4
- Formula:C121H194N46O32
- Molecular Weight:2805.12
SMILES: OC(C=C1)=CC=C1C[C@H](N)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@H](C(O)=O)CCC(O)=O)=O)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O)CC4=CNC5=CC=CC=C45)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Biological Activity: CTP-NBD is a cell permeable specific NFκB peptide inhibitor. CTP-NBD could be used in colitis study[1][2]
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CTP-NBD | CTP-NBD is a cell permeable specific NFκB peptide inhibitor. CTP-NBD could be used in colitis study | |||||||||||||||||||||
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References
- [1]. Lee Y, et al. Colon-targeted celecoxib ameliorates TNBS-induced rat colitis: a potential pharmacologic mechanism and therapeutic advantages. Eur J Pharmacol. 2014 Mar 5;726:49-56 [Content Brief]
- [2]. Hong S, et al. Colon-targeted cell-permeable NFκB inhibitory peptide is orally active against experimental colitis. Mol Pharm. 2012 May 7;9(5):1310-9. [Content Brief]
