1268714-50-6
1268714-50-6
Chemical Structure
Carotuximab
Synonym(s): TRC105; DE-122
- CAS No.: 1268714-50-6
- Formula:N/A
- Molecular Weight:(144.8 kDa)
IUPAC Name: 2-(chloromethyl)-3,4-difluoro-1-methoxybenzene
SMILES: [Carotuximab]
Biological Activity: Carotuximab (TRC105) is a IgG1 monoclonal antibody that blocks endoglin (CD105) and its downstream Smad signaling pathway. Carotuximab has immunomodulatory and antineoplastic actions[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Carotuximab | 99.059% | Carotuximab (TRC105) is a IgG1 monoclonal antibody that blocks endoglin (CD105) and its downstream Smad signaling pathway. Carotuximab has immunomodulatory and antineoplastic actions. | ||||||||||||||||||||
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References
- [1]. Katarina Tripska , et al. Monoclonal anti-endoglin antibody TRC105 (carotuximab) prevents hypercholesterolemia and hyperglycemia-induced endothelial dysfunction in human aortic endothelial cells. Front Med (Lausanne). 2022 Sep 7;9:845918. [Content Brief]
- [2]. June Baik, et al. Therapeutic effect of TRC105 and decitabine combination in AML xenografts. Heliyon. 2020 Oct 13;6(10):e05242. [Content Brief]
