1269826-44-9
1269826-44-9
Chemical Structure
OSBPL7-IN-1
- CAS No.: 1269826-44-9
- Formula:C20H19Cl2F3N2O3
- Molecular Weight:463.28
IUPAC Name: 5-(3,4-dichlorophenyl)-N-((1R,2R)-2-hydroxycyclohexyl)-6-(2,2,2-trifluoroethoxy)nicotinamide
InChIKey: GYXGGHPMGUITOT-IAGOWNOFSA-N
SMILES: FC(F)(F)COC1=C(C2=CC(Cl)=C(C=C2)Cl)C=C(C=N1)C(N[C@H]3[C@@H](CCCC3)O)=O
Biological Activity: OSBPL7-IN-1 is an orally active oxysterol binding protein like 7 (OSBPL7) inhibitor. OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression[1].
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OSBPL7-IN-1 | 99.84% | OSBPL7-IN-1 is an orally active oxysterol binding protein like 7 (OSBPL7) inhibitor. OSBPL7-IN-1 promotes an increase of ABCA1 at the plasma membrane without affecting mRNA expression. | ||||||||||||||||||||
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