127228-54-0
127228-54-0
Chemical Structure
LY309887
- CAS No.: 127228-54-0
- Formula:C19H23N5O6S
- Molecular Weight:449.48
IUPAC Name: (5-(2-((R)-2-amino-4-oxo-3,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidin-6-yl)ethyl)thiophene-2-carbonyl)-L-glutamic acid
InChIKey: GQCXGHHHNACOGE-SKDRFNHKSA-N
SMILES: O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(CC[C@@H](CN2)CC3=C2N=C(N)NC3=O)S1)=O
Biological Activity: LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (GARFT), with a Ki of 6.5 nM, and has antitumor activity.
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LY309887 | 98.23% | LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (GARFT), with a Ki of 6.5 nM, and has antitumor activity. | ||||||||||||||||||||
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LY309887 (Standard) | LY309887 (Standard) is the analytical standard of LY309887 (HY-10818). This product is intended for research and analytical applications. LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (GARFT), with a Ki of 6.5 nM, and has antitumor activity. | |||||||||||||||||||||
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