127345-02-2
127345-02-2
Chemical Structure
LY 245769
- CAS No.: 127345-02-2
- Formula:C25H33F3N8OS
- Molecular Weight:550.64
IUPAC Name: (1S,2R,3E,5Z)-2-((2-(1H-tetrazol-5-yl)ethyl)thio)-1-(3-(1H-tetrazol-5-yl)phenyl)-15,15,15-trifluoropentadeca-3,5-dien-1-ol
InChIKey: AISVBCUPJSXTFQ-ZSFKXVPFSA-N
SMILES: O[C@@H](C1=CC=CC(C2=NN=NN2)=C1)[C@@H](/C=C/C=C\CCCCCCCCC(F)(F)F)SCCC3=NN=NN3
Biological Activity: LY 245769, a omega-trifluoro analog, is a leukotriene E4 (LTE4) inhibitor. LY 245769 interfers the omega-oxidation of N-acetyl-LTE4 and leukotriene B4 (LTB4) with IC50s of 4 μM[1].
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LY 245769 | LY 245769, a omega-trifluoro analog, is a leukotriene E4 (LTE4) inhibitor. LY 245769 interfers the omega-oxidation of N-acetyl-LTE4 and leukotriene B4 (LTB4) with IC50s of 4 μM. | |||||||||||||||||||||
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