127408-30-4
127408-30-4
Chemical Structure
Y-27152
- CAS No.: 127408-30-4
- Formula:C21H22N2O4
- Molecular Weight:366.41
IUPAC Name: N-(benzyloxy)-N-((3S,4R)-6-cyano-3-hydroxy-2,2-dimethylchroman-4-yl)acetamide
InChIKey: RHFUXPCCELGMFC-UXHICEINSA-N
SMILES: CC(N([C@H]1[C@H](O)C(C)(C)OC2=CC=C(C#N)C=C12)OCC3=CC=CC=C3)=O
Biological Activity: Y-27152, a proagent of the KATP (Kir6) channel opener Y-26763, is a long-acting K+ channel opener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state[1][2].
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Y-27152 | Y-27152, a proagent of the KATP (Kir6) channel opener Y-26763, is a long-acting K+ channel opener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state. | |||||||||||||||||||||
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References
- [1]. Nakajima T, et al. Y-27152, a long-acting K+ channel opener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state. J Pharmacol Exp Ther. 1992 May;261(2):730-6. [Content Brief]
- [2]. Fukunari A, et al. Y-26763 protects the canine heart from a stunning injury through opening of the KATP channels. Eur J Pharmacol. 1997 Apr 4;323(2-3):197-204. [Content Brief]
