127966-78-3
Chemical Structure
Histamine H2 receptor antagonist-1
- CAS No.: 127966-78-3
- Formula:C19H30N2O3S
- Molecular Weight:366.52
IUPAC Name: 2-((2-hydroxyethyl)thio)-N-(3-(3-(piperidin-1-ylmethyl)phenoxy)propyl)acetamide
InChIKey: ZRVDLLKTYZXNAD-UHFFFAOYSA-N
SMILES: O=C(NCCCOC1=CC=CC(CN2CCCCC2)=C1)CSCCO
Biological Activity: Antiulcer Agent 3 is a orally active histamine H2-receptor competitive antagonist (pA2 = 6.7). Antiulcer Agent 3 reduces gastric acid secretion. Antiulcer Agent 3 reduces gastric lesions in water-immersion stress-induced ulcer rat models. Antiulcer Agent 3 protects against HCl-ethanol-induced gastric lesions in rats. Antiulcer Agent 3 can be used for the research of peptic ulcer disease[1].
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Histamine H2 receptor antagonist-1 | Antiulcer Agent 3 is a orally active histamine H2-receptor competitive antagonist (pA2 = 6.7). Antiulcer Agent 3 reduces gastric acid secretion. Antiulcer Agent 3 reduces gastric lesions in water-immersion stress-induced ulcer rat models. Antiulcer Agent 3 protects against HCl-ethanol-induced gastric lesions in rats. Antiulcer Agent 3 can be used for the research of peptic ulcer disease. | |||||||||||||||||||||
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