128129-56-6
Chemical Structure
Phlorofucofuroeckol A
- CAS No.: 128129-56-6
- Formula:C30H18O14
- Molecular Weight:602.46
IUPAC Name: 4,9-bis(3,5-dihydroxyphenoxy)benzo[b]benzo[5,6][1,4]dioxino[2,3-e]benzofuran-1,3,6,10,12-pentaol
InChIKey: SLWPBUMYPRVYIJ-UHFFFAOYSA-N
SMILES: OC1=CC(OC2=C(C=C(C(OC3=C4C5=C(O)C=C(O)C(OC6=CC(O)=CC(O)=C6)=C5OC4=C7)=C2OC3=C7O)O)O)=CC(O)=C1
Biological Activity: Phlorofucofuroeckol A is a FcεRI inhibitor with low cytotoxicity toward basophilic leukemia cells. Phlorofucofuroeckol A suppresses binding activity between IgE and FcεRI receptor. Phlorofucofuroeckol A inhibits histamine release from basophilic leukemia cells stimulated by IgE/anti-IgE or calcium ionophore A23187 (HY-N6687). Phlorofucofuroeckol A inhibits β-hexosaminidase release from basophilic leukemia cells stimulated by IgE/DNP-BSA. Phlorofucofuroeckol A can be used for the research of allergy disease[1].
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Phlorofucofuroeckol A | Phlorofucofuroeckol A is a FcεRI inhibitor with low cytotoxicity toward basophilic leukemia cells. Phlorofucofuroeckol A suppresses binding activity between IgE and FcεRI receptor. Phlorofucofuroeckol A inhibits histamine release from basophilic leukemia cells stimulated by IgE/anti-IgE or calcium ionophore A23187 (HY-N6687). Phlorofucofuroeckol A inhibits β-hexosaminidase release from basophilic leukemia cells stimulated by IgE/DNP-BSA. Phlorofucofuroeckol A can be used for the research of allergy disease. | |||||||||||||||||||||
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