1282141-20-1
1282141-20-1
Chemical Structure
XZA-1
- CAS No.: 1282141-20-1
- Formula:C15H16N2O2
- Molecular Weight:256.30
InChIKey: FTUGLCCYHGGXQH-UHFFFAOYSA-N
SMILES: O=C(C1=NOC2=C1CCCCC2)NC3=CC=CC=C3
Biological Activity: XZA-1 is a 3-hydroxyacyl-coenzyme A dehydrogenase (HADH) activator. XZA-1 increases the intracellular level of acetoacetyl-CoA, which in turn induces acetoacetylation modification of Chromobox Protein Homolog 4 (CBX4) at lysine 106 (K106). XZA-1 exhibits antitumor effects in a xenograft model of human hepatocellular carcinoma SMMC7721 cells overexpressing CBX4. XZA-1 can be used for the study of hepatocellular carcinoma[1].
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XZA-1 | 99.59% | XZA-1 is a 3-hydroxyacyl-coenzyme A dehydrogenase (HADH) activator. XZA-1 increases the intracellular level of acetoacetyl-CoA, which in turn induces acetoacetylation modification of Chromobox Protein Homolog 4 (CBX4) at lysine 106 (K106). XZA-1 exhibits antitumor effects in a xenograft model of human hepatocellular carcinoma SMMC7721 cells overexpressing CBX4. XZA-1 can be used for the study of hepatocellular carcinoma. | ||||||||||||||||||||
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