1285920-49-1
Chemical Structure
Desdiacetyl bisacodyl-d13
- CAS No.: 1285920-49-1
- Formula:C18H2D13NO2
- Molecular Weight:290.40
InChIKey: LJROKJGQSPMTKB-MDIFDIPCSA-N
SMILES: OC(C([2H])=C1[2H])=C(C([2H])=C1C([2H])(C2=C(C([2H])=C(C([2H])=C2[2H])O)[2H])C3=C(C([2H])=C(C([2H])=N3)[2H])[2H])[2H]
Biological Activity: Desdiacetyl bisacodyl-d13 is the deuterium labeled Desacetyl bisacodyl (HY-131637). Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl. Desacetyl bisacodyl induces epithelial Cl(-) secretion in rat colon and rectum. Desacetyl bisacodyl evokes several effects at the colon or rectum, including increased mucus and chloride secretion[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Desdiacetyl bisacodyl-d13 | Desdiacetyl bisacodyl-d13 is the deuterium labeled Desacetyl bisacodyl (HY-131637). Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl. Desacetyl bisacodyl induces epithelial Cl(-) secretion in rat colon and rectum. Desacetyl bisacodyl evokes several effects at the colon or rectum, including increased mucus and chloride secretion. | |||||||||||||||||||||
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Desacetyl bisacodyl (Standard) | ≥98% | Desacetyl bisacodyl (Standard) is the analytical standard of Desacetyl bisacodyl. This product is intended for research and analytical applications. Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl. Desacetyl bisacodyl induces epithelial Cl(-) secretion in rat colon and rectum. Desacetyl bisacodyl evokes several effects at the colon or rectum, including increased mucus and chloride secretion. | ||||||||||||||||||||
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Desacetyl bisacodyl | 99.52% | Desacetyl bisacodyl is the active metabolite of the laxative bisacodyl. Desacetyl bisacodyl induces epithelial Cl(-) secretion in rat colon and rectum. Desacetyl bisacodyl evokes several effects at the colon or rectum, including increased mucus and chloride secretion. | ||||||||||||||||||||
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Picosulfate sodium salt hydrate | 98.0% | Picosulfate sodium salt hydrate is the hydrate of Sodium Picosulfate (HY-B0544). Picosulfate sodium salt hydrate is an orally active contact irritant laxative. Picosulfate sodium salt hydrate inhibits the absorption of water and electrolytes, increasing their production. Picosulfate sodium salt hydrate can be used in colonoscopy applications. | ||||||||||||||||||||
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LY56110 | LY56110 is an orally active aromatase inhibitor. LY56110 inhibits P-450-dependent p-nitroanisole O-demethylation and ethylmorphine N-demethylation in hepatic microsomes isolated from rat, with the IC50 of 2.5 and 11 μΜ, respectively. LY56110 can be used for neurological disorder study. | |||||||||||||||||||||
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Sodium Picosulfate | 98.0% | Sodium Picosulfate (Sodium Picosulphate) is a contact irritant laxative with oral activity. Sodium Picosulfate inhibits the absorption of water and electrolytes, increasing their production. Sodium Picosulfate can be used in colonoscopy applications. | ||||||||||||||||||||
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Bisacodyl | 99.71% | Bisacodyl is a stimulant laxative agent that works directly on the colon to produce a bowel movement. Bisacodyl increases the secretion of PGE2 by direct activation of colon macrophages. PGE2 acts as a paracrine factor and decreases the expression of AQP3 in the colon, which inhibits water transfer from the luminal to the vascular side and leads to a laxative effect. | ||||||||||||||||||||
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Tris(4-aminophenyl)methane | 98.0% | Tris(4-aminophenyl)methane is a triphenylmethane dye. Tris(4-aminophenyl)methane is a weak HCV helicase inhibitor. | ||||||||||||||||||||
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4,4'-Dihydroxybenzophenone | 99.33% | 4,4'-Dihydroxybenzophenone is a type of phenolic ultraviolet absorber and a drug intermediate for synthesis of various anticancer active compounds (such as Sivifene (HY-14801)). 4,4'-Dihydroxybenzophenone binds to the active site of trypsin with binding constants (KA = 7.59 x 105 L/moL) and leads to abnormal structure of trypsin, suggesting that long-term intake may affect the digestive function of the human body. 4,4’-dihydroxybenzophenone has a relatively low toxicity to Chlorella vulgaris and a moderate toxicity to Daphnia magna. | ||||||||||||||||||||
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Bisphenol E | 99.90% | Bisphenol E (4,4'-Ethylidenediphenol) is a biochemical reagent. | ||||||||||||||||||||
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Phenolphthalol | Phenolphthalol is a laxative in agent preparations and also estrogenically active. | |||||||||||||||||||||
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4-(Di(1H-pyrrol-2-yl)methyl)pyridine | 4-(Di(1H-pyrrol-2-yl)methyl)pyridine (5-(4-Pyridyl)dipyrromethane) is a metal-organic framework (MOF). | |||||||||||||||||||||
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