128625-52-5
Chemical Structure
(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate
Synonym(s): Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
- CAS No.: 128625-52-5
- Formula:C18H28F6N6OP2
- Molecular Weight:520.39
IUPAC Name: ((1H-benzo[d][1,2,3]triazol-1-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V)
InChIKey: VIAFLMPQBHAMLI-UHFFFAOYSA-N
SMILES: F[P-](F)(F)(F)(F)F.C12=CC=CC=C1N=NN2O[P+](N3CCCC3)(N4CCCC4)N5CCCC5
Biological Activity: (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent and BOP analog. (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate promotes the reaction of amino and carboxyl groups to form peptide bonds. (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate can be used in the synthesis of peptide compounds[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate | 98.0% | (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent and BOP analog. (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate promotes the reaction of amino and carboxyl groups to form peptide bonds. (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate can be used in the synthesis of peptide compounds. | ||||||||||||||||||||
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References
- [1]. Coste J, et al., PyBOP®: A new peptide coupling reagent devoid of toxic by-product[J]. Tetrahedron Letters, 1990, 31(2): 205-208.
- [2]. Frérot E, et al. PyBOP® and PyBroP: Two reagents for the difficult coupling of the α, α-dialkyl amino acid, Aib. Tetrahedron, 1991, 47(2): 259-270.
- [3]. Santos Oliveira AJM, et al. Amides Derived from Vanillic Acid: Coupling Reactions, Antimicrobial Evaluation, and Molecular Docking. Biomed Res Int. 2019 Apr 15;2019:9209676. [Content Brief]
