128700-97-0
128700-97-0
Chemical Structure
Gingerenone A
- CAS No.: 128700-97-0
- Formula:C21H24O5
- Molecular Weight:356.41
IUPAC Name: (E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hept-4-en-3-one
InChIKey: FWDXZNKYDTXGOT-GQCTYLIASA-N
SMILES: O=C(/C=C/CCC1=CC=C(O)C(OC)=C1)CCC2=CC=C(O)C(OC)=C2
Biological Activity: Gingerenone A is an Nrf2-Gpx4 activator that can induce Ferroptosis in liver damage with oral activity. Gingerenone A has anti-inflammatory, anti-diabetic, anti-tumor, and pro-aging effects in mice[1][2][3][4].
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Gingerenone A | 99.95% | Gingerenone A is an Nrf2-Gpx4 activator that can induce Ferroptosis in liver damage with oral activity. Gingerenone A has anti-inflammatory, anti-diabetic, anti-tumor, and pro-aging effects in mice. | ||||||||||||||||||||
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Gingerenone A (Standard) | ≥98% | Gingerenone A (Standard) is the analytical standard of Gingerenone A. This product is intended for research and analytical applications. Gingerenone A is an Nrf2-Gpx4 activator that can induce Ferroptosis in liver damage with oral activity. Gingerenone A has anti-inflammatory, anti-diabetic, anti-tumor, and pro-aging effects in mice. | ||||||||||||||||||||
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References
- [1]. Junhong Chen, et al. Gingerenone A Sensitizes the Insulin Receptor and Increases Glucose Uptake by Inhibiting the Activity of p70 S6 Kinase. Mol Nutr Food Res.2018 Dec;62(23):e1800709. [Content Brief]
- [2]. Sujin Suk, et al. Gingerenone A, a polyphenol present in ginger, suppresses obesity and adipose tissue inflammation in high-fat diet-fed mice. Mol Nutr Food Res. 2017 Oct;61(10):10.1002/mnfr.201700139. [Content Brief]
- [3]. Yu TJ, et al. Gingerenone A Induces Antiproliferation and Senescence of Breast Cancer Cells. Antioxidants (Basel). 2022 Mar 19;11(3):587. [Content Brief]
- [4]. Chen Y, et al. Gingerenone A Alleviates Ferroptosis in Secondary Liver Injury in Colitis Mice via Activating Nrf2-Gpx4 Signaling Pathway. J Agric Food Chem. 2022 Oct 5;70(39):12525-12534. [Content Brief]
