129468-28-6
129468-28-6
Chemical Structure
BNTX
Synonym(s): 7-Benzylidenenaltrexone
- CAS No.: 129468-28-6
- Formula:C27H27NO4
- Molecular Weight:429.51
InChIKey: WXOUFNFMPVMGFZ-XEGDMQTMSA-N
SMILES: O[C@]12[C@@]34C5=C(C[C@@]2([H])N(CC4)CC6CC6)C=CC(O)=C5O[C@@]3([H])C(/C(C1)=C\C7=CC=CC=C7)=O
Biological Activity: BNTX (7-Benzylidenenaltrexone) is a highly selective δ1 opioid receptor antagonist. BNTX selectively antagonizes the antinociceptive activity mediated by spinal δ1 opioid receptors, and does not alter the antinociceptive effects mediated by δ2, μ or κ opioid receptors at selective doses[1].
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BNTX | BNTX (7-Benzylidenenaltrexone) is a highly selective δ1 opioid receptor antagonist. BNTX selectively antagonizes the antinociceptive activity mediated by spinal δ1 opioid receptors, and does not alter the antinociceptive effects mediated by δ2, μ or κ opioid receptors at selective doses. | |||||||||||||||||||||
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