129724-43-2
129724-43-2
Chemical Structure
2',4'-Dihydroxy-3',6'-dimethoxychalcone
- CAS No.: 129724-43-2
- Formula:C17H16O5
- Molecular Weight:300.31
IUPAC Name: (E)-1-(2,4-dihydroxy-3,6-dimethoxyphenyl)-3-phenylprop-2-en-1-one
InChIKey: BXMWIRIMYNWIGQ-CMDGGOBGSA-N
SMILES: O=C(C1=C(OC)C=C(O)C(OC)=C1O)/C=C/C2=CC=CC=C2
Biological Activity: 2',4'-Dihydroxy-3',6'-dimethoxychalcone is a natural product that can be isolated from Polygonum Lapathifolium. 2',4'-Dihydroxy-3',6'-dimethoxychalcone inhibits the growth of CCRF-CEM leukaemia cells and CEM/ADR5000 cells, with IC50 values of 10.67 and 18.60 μM, respectively[1][2].
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2',4'-Dihydroxy-3',6'-dimethoxychalcone | 2',4'-Dihydroxy-3',6'-dimethoxychalcone is a natural product that can be isolated from Polygonum Lapathifolium. 2',4'-Dihydroxy-3',6'-dimethoxychalcone inhibits the growth of CCRF-CEM leukaemia cells and CEM/ADR5000 cells, with IC50 values of 10.67 and 18.60 μM, respectively. | |||||||||||||||||||||
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References
- [1]. Ahmed M, et al. Isoflavan-4-ol, dihydrochalcone and chalcone derivatives from Polygonum Lapathifolium. Phytochemistry, 1990, 29(6):2009-2011.
- [2]. Nkuété AH, et al. Anti-leukemia activity of semi-synthetic phenolic derivatives from Polygonum limbatum Meisn. Chem Cent J. 2015 Jun 24;9:40. [Content Brief]
