1300031-52-0
1300031-52-0
Chemical Structure
GSK1324726A
Synonym(s): I-BET726
- CAS No.: 1300031-52-0
- Formula:C25H23ClN2O3
- Molecular Weight:434.91
IUPAC Name: 4-((2S,4R)-1-acetyl-4-((4-chlorophenyl)amino)-2-methyl-1,2,3,4-tetrahydroquinolin-6-yl)benzoic acid
InChIKey: FAWSUKOIROHXAP-NPMXOYFQSA-N
SMILES: ClC1=CC=C(N[C@H]2C3=C(C=CC(C4=CC=C(C(O)=O)C=C4)=C3)N(C(C)=O)[C@@H](C)C2)C=C1
Biological Activity: GSK1324726A is a novel, potent, and selective inhibitor of BET proteins with high affinity to BRD2 (IC50=41 nM), BRD3 (IC50=31 nM), and BRD4 (IC50=22 nM).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
GSK1324726A | 99.92% | GSK1324726A is a novel, potent, and selective inhibitor of BET proteins with high affinity to BRD2 (IC50=41 nM), BRD3 (IC50=31 nM), and BRD4 (IC50=22 nM). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
