130610-93-4
130610-93-4
Chemical Structure
Niravoline
Synonym(s): RU51599
- CAS No.: 130610-93-4
- Formula:C22H25N3O3
- Molecular Weight:379.45
IUPAC Name: N-methyl-2-(3-nitrophenyl)-N-((1S,2S)-2-(pyrrolidin-1-yl)-2,3-dihydro-1H-inden-1-yl)acetamide
InChIKey: ZSDAQBWGAOKTSI-UNMCSNQZSA-N
SMILES: O=C(N([C@@H]1[C@@H](N2CCCC2)CC3=C1C=CC=C3)C)CC4=CC=CC([N+]([O-])=O)=C4
Biological Activity: Niravoline (RU51599) is an arginine vasopressin (AVP) release inhibitor and a selective kappa opioid receptor agonist. Niravoline has a pure water diuresis effect without associated electrolyte excretion. Niravoline can reduce brain oedema following transient forebrain ischaemia in rats[1].
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Niravoline | Niravoline (RU51599) is an arginine vasopressin (AVP) release inhibitor and a selective kappa opioid receptor agonist. Niravoline has a pure water diuresis effect without associated electrolyte excretion. Niravoline can reduce brain oedema following transient forebrain ischaemia in rats. | |||||||||||||||||||||
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