1309573-60-1
Chemical Structure
DL-alpha-Tocopherol methoxypolyethylene glycol succinate
Synonym(s): TPGS-750-M
- CAS No.: 1309573-60-1
- Formula:(C2H4O)nC34H56O5
- Molecular Weight:N/A
SMILES: CC1=C(CCC(CCCC(C)CCCC(C)CCCC(C)C)(C)O2)C2=C(C)C(C)=C1OC(CCC(OCCOC)=O)=O.[n]
Biological Activity: DL-alpha-Tocopherol methoxypolyethylene glycol succinate (TPGS-750-M) is an amphiphile, acts as a surfactant. DL-alpha-Tocopherol methoxypolyethylene glycol succinate has a positive effect on Suzuki-Miyaura cross coupling. DL-alpha-Tocopherol methoxypolyethylene glycol succinate increases the styrene titer. DL-alpha-Tocopherol methoxypolyethylene glycol succinate is used in the stability test of NPYM-modified drugs in biological fluids[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DL-alpha-Tocopherol methoxypolyethylene glycol succinate | 98.14% | DL-alpha-Tocopherol methoxypolyethylene glycol succinate (TPGS-750-M) is an amphiphile, acts as a surfactant. DL-alpha-Tocopherol methoxypolyethylene glycol succinate has a positive effect on Suzuki-Miyaura cross coupling. DL-alpha-Tocopherol methoxypolyethylene glycol succinate increases the styrene titer. DL-alpha-Tocopherol methoxypolyethylene glycol succinate is used in the stability test of NPYM-modified drugs in biological fluids. | ||||||||||||||||||||
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References
- [1]. Lipshutz BH, et al. TPGS-750-M: a second-generation amphiphile for metal-catalyzed cross-couplings in water at room temperature. J Org Chem. 2011 Jun 3;76(11):4379-91. [Content Brief]
- [2]. Cetin A, et al. Aqueous TPGS-750-M-mediated synthesis of pyrano [2, 3-c]-pyrazoles: a sustainable and efficient approach[J]. Research on Chemical Intermediates, 2024: 1-14.
- [3]. Wu B, et al. Merging biocatalysis, flow, and surfactant chemistry: innovative synthesis of an FXI (Factor XI) inhibitor[J]. Organic Process Research & Development, 2020, 24(11): 2780-2788.
- [4]. Ermini E, et al. A novel bioresponsive self-immolative spacer based on aza-quinone methide reactivity for the controlled release of thiols, phenols, amines, sulfonamides or amides. Chem Sci. 2024 Apr 2;15(16):6168-6177. [Content Brief]
- [5]. Maaskant R V, et al. Merging whole‐cell biosynthesis of styrene and transition‐metal catalyzed derivatization reactions. ChemCatChem, 2021, 13(6): 1607-1613.
