131023-24-0
Chemical Structure
P60v-src(137-157)
- CAS No.: 131023-24-0
- Formula:C111H168N30O35
- Molecular Weight:2482.70
InChIKey: VNWKTOKETHGBQD-UHFFFAOYSA-N
SMILES: O=C(N[C@@H](C)C(N1[C@@H](CCC1)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@@H](CC5=CC=CC=C5)C(NCC(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N
Biological Activity: P60v-src(137-157) is a synthetic peptide that inhibits the tyrosine kinase activity of p60v-src (IC50: 7.5 μM)[1][2].
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P60v-src(137-157) | P60v-src(137-157) is a synthetic peptide that inhibits the tyrosine kinase activity of p60v-src (IC50: 7.5 μM). | |||||||||||||||||||||
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References
- [1]. Sato K, et al. A synthetic peptide corresponding to residues 137 to 157 of p60v-src inhibits tyrosine-specific protein kinases. Biochem Biophys Res Commun. 1990 Sep 28;171(3):1152-9. [Content Brief]
- [2]. Wijetunge S, et al. pp60c-src increases voltage-operated calcium channel currents in vascular smooth muscle cells. Biochem Biophys Res Commun. 1995 Dec 26;217(3):1039-44. [Content Brief]
