1311612-43-7
1311612-43-7
Chemical Structure
ORS-22
- CAS No.: 1311612-43-7
- Formula:C16H18N6OS
- Molecular Weight:342.42
InChIKey: IRKHRQUONLOLHY-UHFFFAOYSA-N
SMILES: CN(CC(N1CCN2C(C1)=NN=C2C)=O)C3=NC4=C(S3)C=CC=C4
Biological Activity: ORS-22 is an immunomodulator with a Kd value of 9.2 nM for human LILRB4. ORS-22 binds directly to the extracellular domain of LILRB4, reverses immunosuppression, restores cytotoxic T cell function, recovers cytokine production, and reduces tumor cell viability. ORS-22 can be used in research related to colorectal cancer and acute myeloid leukemia[1].
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ORS-22 | ORS-22 is an immunomodulator with a Kd value of 9.2 nM for human LILRB4. ORS-22 binds directly to the extracellular domain of LILRB4, reverses immunosuppression, restores cytotoxic T cell function, recovers cytokine production, and reduces tumor cell viability. ORS-22 can be used in research related to colorectal cancer and acute myeloid leukemia. | |||||||||||||||||||||
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