1312815-93-2
1312815-93-2
Chemical Structure
PF-4693627
- CAS No.: 1312815-93-2
- Formula:C26H29Cl2N3O3
- Molecular Weight:502.43
IUPAC Name: 1-(5-chloro-6-(4-chlorophenyl)benzo[d]oxazol-2-yl)-N-((1S,3S)-3-(hydroxymethyl)cyclohexyl)piperidine-4-carboxamide
InChIKey: CPDNPVKDQXLYHO-JXFKEZNVSA-N
SMILES: O=C(C1CCN(C2=NC3=CC(Cl)=C(C4=CC=C(Cl)C=C4)C=C3O2)CC1)N[C@@H]5C[C@@H](CO)CCC5
Biological Activity: PF-4693627 is a potent, selective and orally bioavailable microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor (IC50=3 nM) for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PF-4693627 | 99.63% | PF-4693627 is a potent, selective and orally bioavailable microsomal prostaglandin E synthase-1 (mPGES-1) inhibitor (IC50=3 nM) for the treatment of inflammation caused by osteoarthritis (OA) and rheumatoid arthritis (RA). | ||||||||||||||||||||
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