1313019-65-6
1313019-65-6
Chemical Structure
STAT3-IN-48
- CAS No.: 1313019-65-6
- Formula:C21H13ClF3N3O2
- Molecular Weight:431.80
IUPAC Name: 1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-(4-cyanophenoxy)phenyl)urea
InChIKey: HVPZDXDXIQZKHU-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(OC2=CC=C(C#N)C=C2)C=C1)NC3=CC=C(Cl)C(C(F)(F)F)=C3
Biological Activity: STAT3-IN-48 is a Sorafenib analogue and potently inhibits the phosphorylation of STAT3. STAT3-IN-48 induces cell apoptosis through SHP-1 dependent STAT3 inactivation. STAT3-IN-48 does not inhibit kinase activity and has anticancer effects[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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STAT3-IN-48 | 98.64% | STAT3-IN-48 is a Sorafenib analogue and potently inhibits the phosphorylation of STAT3. STAT3-IN-48 induces cell apoptosis through SHP-1 dependent STAT3 inactivation. STAT3-IN-48 does not inhibit kinase activity and has anticancer effects. | ||||||||||||||||||||
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