1315378-67-6
Chemical Structure
pep2-EVKI
Synonym(s): YNVYGIEEVKI
- CAS No.: 1315378-67-6
- Formula:C62H95N13O19
- Molecular Weight:1326.49
IUPAC Name: (2S,5S,8S,11S,14S)-14-((2S,8S,11S,14S,17S)-17-amino-14-(2-amino-2-oxoethyl)-2-((S)-sec-butyl)-8-(4-hydroxybenzyl)-18-(4-hydroxyphenyl)-11-isopropyl-4,7,10,13,16-pentaoxo-3,6,9,12,15-pentaazaoctadecanamido)-5-(4-aminobutyl)-2-((S)-sec-butyl)-11-(2-carboxyethyl)-8-isopropyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazaheptadecanedioic acid
InChIKey: KGQYILLVACJAQP-XMCCVONBSA-N
SMILES: OC(C=C1)=CC=C1C[C@@H](C(NCC(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@H](C(O)=O)[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)NC([C@H](C(C)C)NC([C@H](CC(N)=O)NC([C@@H](N)CC2=CC=C(O)C=C2)=O)=O)=O
Biological Activity: pep2-EVKI (YNVYGIEEVKI) is an inhibitor peptide that selectively blocks PICK1 interactions, caused the opposite effects on synaptic AMPAR function to PICK1 expression[1].
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pep2-EVKI | pep2-EVKI (YNVYGIEEVKI) is an inhibitor peptide that selectively blocks PICK1 interactions, caused the opposite effects on synaptic AMPAR function to PICK1 expression. | |||||||||||||||||||||
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