1315378-75-6
Chemical Structure
MNI-caged kainate
- CAS No.: 1315378-75-6
- Formula:C14H17N3O6
- Molecular Weight:323.30
IUPAC Name: (R)-4-(4-methoxy-7-nitroindolin-1-yl)-2-(methylamino)-4-oxobutanoic acid
InChIKey: MUCRWOILMOHLGD-SECBINFHSA-N
SMILES: O=C(O)[C@H](NC)CC(N1CCC2=C1C([N+]([O-])=O)=CC=C2OC)=O
Biological Activity: MNI-caged kainate is a photoprotected neuroactive amino acid with the activity to generate large inward currents. MNI-caged kainate can be released at the resting membrane potential of Purkinje cells and generate significant inward currents. The release of MNI-caged kainate results in approximately 40% of the current being generated through AMPA receptor activation. MNI-caged kainate is used to study fast synaptic receptor mechanisms. The photorelease time of MNI-caged kainate is in the sub-microsecond range, making it suitable for investigating the mechanisms of fast synaptic transmission[1].
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MNI-caged kainate | MNI-caged kainate is a photoprotected neuroactive amino acid with the activity to generate large inward currents. MNI-caged kainate can be released at the resting membrane potential of Purkinje cells and generate significant inward currents. The release of MNI-caged kainate results in approximately 40% of the current being generated through AMPA receptor activation. MNI-caged kainate is used to study fast synaptic receptor mechanisms. The photorelease time of MNI-caged kainate is in the sub-microsecond range, making it suitable for investigating the mechanisms of fast synaptic transmission. | |||||||||||||||||||||
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