1315485-91-6
1315485-91-6
Chemical Structure
oJak-989
- CAS No.: 1315485-91-6
- Formula:C15H18N4O2
- Molecular Weight:286.34
IUPAC Name: (R)-1-(1-((S)-tetrahydro-2H-pyran-3-yl)-1,5-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)ethan-1-ol
InChIKey: VSKQOMHTMYZRLK-ZJUUUORDSA-N
SMILES: [C@H](C)(O)C=1N(C2=C3C(NC=C2N1)=NC=C3)[C@H]4CCCOC4
Biological Activity: oJak-989 is a selective JAK1 inhibitor with a Ki of 2.8 nM for JAK1, 110 nM for JAK3, and 31 nM for TYK2. oJak-989 is applicable to the research of inflammatory diseases[1].
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oJak-989 | oJak-989 is a selective JAK1 inhibitor with a Ki of 2.8 nM for JAK1, 110 nM for JAK3, and 31 nM for TYK2. oJak-989 is applicable to the research of inflammatory diseases. | |||||||||||||||||||||
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