131740-09-5
131740-09-5
Chemical Structure
Flavopiridol Hydrochloride
Synonym(s): Alvocidib Hydrochloride; L86-8275 Hydrochloride; HMR-1275 Hydrochloride
- CAS No.: 131740-09-5
- Formula:C21H21Cl2NO5
- Molecular Weight:438.30
IUPAC Name: 2-(2-chlorophenyl)-5,7-dihydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4H-chromen-4-one hydrochloride
InChIKey: LGMSNQNWOCSPIK-LWHGMNCYSA-N
SMILES: O=C1C2=C(C=C(C([C@]3([H])[C@H](O)CN(C)CC3)=C2OC(C4=CC=CC=C4Cl)=C1)O)O.[H]Cl
Biological Activity: Flavopiridol Hydrochloride (Alvocidib Hydrochloride) is a broad inhibitor of CDK, competing with ATP to inhibit CDKs including CDK1, CDK2, CDK4 with IC50s of 30, 170, 100 nM, respectively.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Flavopiridol Hydrochloride | 99.73% | Flavopiridol Hydrochloride (Alvocidib Hydrochloride) is a broad inhibitor of CDK, competing with ATP to inhibit CDKs including CDK1, CDK2, CDK4 with IC50s of 30, 170, 100 nM, respectively. | ||||||||||||||||||||
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