13191-15-6
13191-15-6
Chemical Structure
Cytarabine triphosphate
Synonym(s): Ara-CTP
- CAS No.: 13191-15-6
- Formula:C9H16N3O14P3
- Molecular Weight:483.16
IUPAC Name: ((2R,3S,4S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
InChIKey: PCDQPRRSZKQHHS-CCXZUQQUSA-N
SMILES: O[C@@H]1[C@@](N2C(N=C(C=C2)N)=O)([H])O[C@@H]([C@H]1O)COP(OP(OP(O)(O)=O)(O)=O)(O)=O
Biological Activity: Cytarabine triphosphate (Ara-CTP), an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine[1].
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Cytarabine triphosphate | Cytarabine triphosphate (Ara-CTP), an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine. | |||||||||||||||||||||
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