1320211-70-8
1320211-70-8
Chemical Structure
(R)-Pralatrexate
- CAS No.: 1320211-70-8
- Formula:C23H23N7O5
- Molecular Weight:477.47
IUPAC Name: (4-((R)-1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoyl)-L-glutamic acid
InChIKey: OGSBUKJUDHAQEA-ZBFHGGJFSA-N
SMILES: O=C(CC[C@H](NC(C1=CC=C(C=C1)[C@H](CC#C)CC2=NC3=C(N=C(N=C3N=C2)N)N)=O)C(O)=O)O
Biological Activity: (R)-Pralatrexate is the (R)-enantiomer of Pralatrexate (HY-10446). Pralatrexate is an antifolate and is a potent dihydrofolate reductasean (DHFR) inhibitor[1].
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(R)-Pralatrexate | (R)-Pralatrexate is the (R)-enantiomer of Pralatrexate (HY-10446). Pralatrexate is an antifolate and is a potent dihydrofolate reductasean (DHFR) inhibitor. | |||||||||||||||||||||
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