132326-72-8
Chemical Structure
Influenza NP (147-155)
- CAS No.: 132326-72-8
- Formula:C48H82N16O14
- Molecular Weight:1107.26
IUPAC Name: L-threonyl-L-tyrosyl-L-glutaminyl-L-arginyl-L-threonyl-L-arginyl-L-alanyl-L-leucyl-L-valine
InChIKey: WOUNFMMWMQKJJQ-WNGIYMBZSA-N
SMILES: O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@H](O)C)N
Biological Activity: Influenza NP (147-155) is an MHC class I-restricted cytotoxic T lymphocyte (CTL) epitope derived from the nucleoprotein of influenza A virus. Influenza NP (147-155) activates CTLs through peptide-MHC-I/TCR recognition, enabling CTLs to lyse target cells, and is efficiently recognized by Kd-restricted CTLs. Influenza NP (147-155) prevents lethal heterosubtypic influenza A virus infection. Influenza NP (147-155) can be used in influenza-related research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Influenza NP (147-155) | Influenza NP (147-155) is an MHC class I-restricted cytotoxic T lymphocyte (CTL) epitope derived from the nucleoprotein of influenza A virus. Influenza NP (147-155) activates CTLs through peptide-MHC-I/TCR recognition, enabling CTLs to lyse target cells, and is efficiently recognized by Kd-restricted CTLs. Influenza NP (147-155) prevents lethal heterosubtypic influenza A virus infection. Influenza NP (147-155) can be used in influenza-related research. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. McGee MC, et al. Evolutionary conservation and positive selection of influenza A nucleoprotein CTL epitopes for universal vaccination. Journal of medical virology. 2022 Jun;94(6):2578-2587.
- [2]. Falk K, et al. Identification of naturally processed viral nonapeptides allows their quantification in infected cells and suggests an allele-specific T cell epitope forecast. The Journal of experimental medicine. 1991 Aug 01;174(2):425-34.
