132373-81-0
Chemical Structure
Vamicamide
Synonym(s): FK-176
- CAS No.: 132373-81-0
- Formula:C18H23N3O
- Molecular Weight:297.39
IUPAC Name: (2R,4R)-4-(dimethylamino)-2-phenyl-2-(pyridin-2-yl)pentanamide
InChIKey: BWNLUIXQIHPUGO-RDTXWAMCSA-N
SMILES: O=C(N)[C@@](C1=CC=CC=C1)(C[C@H](N(C)C)C)C2=NC=CC=C2
Biological Activity: Vamicamide (FK-176) is an orally active competitive mAChR antagonist that inhibits contractions induced by cholinergic nerve stimulation by preventing mAChR agonists from binding to mAChR. Vamicamide exhibits a good anti-bladder spasm effect, with a pA2 value of 6.82 in bladder tissue. Vamicamide can be used in research within the field of neurological diseases[1].
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Vamicamide | Vamicamide (FK-176) is an orally active competitive mAChR antagonist that inhibits contractions induced by cholinergic nerve stimulation by preventing mAChR agonists from binding to mAChR. Vamicamide exhibits a good anti-bladder spasm effect, with a pA2 value of 6.82 in bladder tissue. Vamicamide can be used in research within the field of neurological diseases. | |||||||||||||||||||||
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