1325212-97-2
1325212-97-2
Chemical Structure
GSK2245035 maleate
- CAS No.: 1325212-97-2
- Formula:C24H38N6O6
- Molecular Weight:506.60
InChIKey: MWVXFHFYGZBEBN-DASCVMRKSA-N
SMILES: OC(/C=C\C(O)=O)=O.O=C(N(C1=NC(O[C@@H](C)CCC)=N2)CCCCCN3CCCCC3)NC1=C2N
Biological Activity: GSK2245035 maleate is a highly potent and selective intranasal Toll-Like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 maleate has pEC50s of 9.3 and 6.5 for IFNα and TFNα. GSK2245035 maleate effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures. GSK2245035 maleate is used for asthma[1].
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GSK2245035 maleate | GSK2245035 maleate is a highly potent and selective intranasal Toll-Like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 maleate has pEC50s of 9.3 and 6.5 for IFNα and TFNα. GSK2245035 maleate effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures. GSK2245035 maleate is used for asthma. | |||||||||||||||||||||
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