133240-38-7
133240-38-7
Chemical Structure
L 158338
- CAS No.: 133240-38-7
- Formula:C24H23N7
- Molecular Weight:409.49
IUPAC Name: 3-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-7-methyl-2-propyl-3H-imidazo[4,5-b]pyridine
InChIKey: CYUMNDVYHILLEX-UHFFFAOYSA-N
SMILES: CCCC1=NC2=C(C)C=CN=C2N1CC3=CC=C(C=C3)C4=C(C=CC=C4)C5=NN=NN5
Biological Activity: L 158338 is an angiotensin II receptor antagonist. L 158338 alleviates acidosis and increases coronary blood flow during the ischemic period and increases coronary blood flow during the reperfusion period. L 158338 can be used to study myocardial injury during ischemia and reperfusion[1].
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L 158338 | L 158338 is an angiotensin II receptor antagonist. L 158338 alleviates acidosis and increases coronary blood flow during the ischemic period and increases coronary blood flow during the reperfusion period. L 158338 can be used to study myocardial injury during ischemia and reperfusion. | |||||||||||||||||||||
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References
- [1]. Werrmann J G, et al. Comparison of effects of angiotensin-converting enzyme inhibition with those of angiotensin II receptor antagonism on functional and metabolic recovery in postischemic working rat heart as studied by [31P] nuclear magnetic resonance[J]. Journal of cardiovascular pharmacology, 1994, 24(4): 573-586. [Content Brief]
