1332485-18-3
Chemical Structure
BI-5756
- CAS No.: 1332485-18-3
- Formula:C27H32F3NO3
- Molecular Weight:475.54
InChIKey: HKASDKLLEVWKJA-YADARESESA-N
SMILES: CC(C1=NC(CC(C)(C[C@@H]2O)C)=C2C3=C1[C@@H](C4=CC=C(C=C4)C(F)(F)F)OC35CCOCC5)C
Biological Activity: BI-5756 is a CETP inhibitor and cannabinoid receptor 1 (CB1) agonist. BI-5756 can significantly increase HDL-C levels and reduce LDL-C levels. BI-5756 can also enhance the function of regulatory T cells while maintaining T cell-mediated anti-tumor activity. BI-5756 can directly inhibit the growth of tumor cells and upregulate the expression of MHC I, MHC II, and CD80 on tumor cells. BI-5756 has a protective effect in graft-versus-host disease models. BI-5756 can be used in research on tumors, graft-versus-host disease, and metabolic diseases[1].
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BI-5756 | BI-5756 is a CETP inhibitor and cannabinoid receptor 1 (CB1) agonist. BI-5756 can significantly increase HDL-C levels and reduce LDL-C levels. BI-5756 can also enhance the function of regulatory T cells while maintaining T cell-mediated anti-tumor activity. BI-5756 can directly inhibit the growth of tumor cells and upregulate the expression of MHC I, MHC II, and CD80 on tumor cells. BI-5756 has a protective effect in graft-versus-host disease models. BI-5756 can be used in research on tumors, graft-versus-host disease, and metabolic diseases. | |||||||||||||||||||||
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